Transplantation atherosclerosis
نویسندگان
چکیده
منابع مشابه
Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation
BACKGROUND The CX3C chemokine receptor CX3CR1 is expressed on monocytes as well as tissue resident cells, such as smooth muscle cells (SMCs). Its role in atherosclerotic tissue remodeling of the aorta after transplantation has not been investigated. METHODS We here have orthotopically transplanted infrarenal Cx3cr1-/-Apoe-/- and Cx3cr1+/+Apoe-/- aortic segments into Apoe-/-mice, as well as Ap...
متن کاملAtherosclerosis after kidney transplantation: changes of intima-media thickness of carotids during early posttransplant period.
INTRODUCTION The aim of this study was to evaluate atherosclerotic changes in the carotid artery following kidney transplantation. MATERIALS AND METHODS Twenty-six nonsmoker kidney allograft recipients who did not have cardiovascular disease or diabetes mellitus were enrolled in the study. The carotid intima-media thickness (IMT) was measured at 12 points using B-mode ultrasonography. The mea...
متن کاملHypercholesterolemia increases coronary endothelial dysfunction, lipid content, and accelerated atherosclerosis after heart transplantation.
Hyperlipidemia may increase endothelial damage and promote accelerated atherogenesis in graft coronary vasculopathy. To study the effects of hypercholesterolemia on coronary endothelial dysfunction, intimal hyperplasia, and lipid content, a porcine model of heterotopic heart transplantation, allowing nonacute rejection without immunosuppressive drugs, was used. A high cholesterol diet was fed t...
متن کاملDevelopment of transplantation vasculopathy and progression of donor-transmitted atherosclerosis: comparison by serial intravascular ultrasound imaging.
BACKGROUND Transplant coronary artery disease is a combination of atherosclerosis transmitted from the donor and new lesions of allograft vasculopathy. We sought to determine the morphological characteristics of allograft vasculopathy and differentiate it from donor-transmitted atherosclerosis with serial intravascular ultrasound. METHODS AND RESULTS Intravascular ultrasound examination was p...
متن کاملA longitudinal study of inflammation, CKD-mineral bone disorder, and carotid atherosclerosis after renal transplantation.
BACKGROUND AND OBJECTIVES The role of reversibility of nontraditional risk factors, like inflammation and CKD-mineral bone disorder, in the reduction of cardiovascular risk after renal transplantation is still scarcely defined. DESIGN, SETTING, PARTICIPANTS, AND MEASUREMENTS The longitudinal relationship between C-reactive protein, CKD-mineral bone disorder biomarkers, and intima media thickn...
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ژورنال
عنوان ژورنال: Journal of Internal Medicine
سال: 1996
ISSN: 0954-6820,1365-2796
DOI: 10.1046/j.1365-2796.1996.65874000.x